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Viagra is used for the treatment of male impotency. The active ingredient in Viagra is a specific inhibitor of phosphodiesterase 5. Phosphodiesterase 5 (PDE5) cleaves the ring form of cyclic GMP (cGMP) a cellular second messenger similar to cAMP. The inhibition of the phosphodiesterase allows for the persistence of cGMP which promotes the effects of cGMP production. In this case, it allows for increased blood flow into the penis which may result in an erection.
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