Cool! Yes, we would definitely need more players.
I don't know what I was thinking when I wrote my previous post. While I love Pathfinder, I had previously conclusively determined that 4e was almost certainly the best chassis to emulate Diablo. So, assuming we can get more players, we'd have to decide how we want to do it. If you all just want a gritty hack-and-slash fest with a Diablo theme, I've got some ideas for mechanically generating randomly-seeded dungeons. However, I'm more interested in narrative games, and would even be interested in running something mapless if people were into that. I've got plenty of ideas for an original story that takes place after the events of Diablo II: Lord of Destruction that diverges from Diablo III. It would also be interesting to explore what else might be happening in the world concurrent with the events of the second game. If we get some more interest, I'll throw up a couple of proposals to see what people are interested in.