As mentioned in the other thread, I'm playing in a Witchcraft game, one where magic and the supernatural are out in the open. Think of a cross between GURPS Technomancer, a modern-day Shadowrun, and Poul Anderson's Operation Chaos. It's otherwise not too unlike the real world, with some interesting variations due to the supernatural content (i.e. "vamp dust" is a nasty street drug that targets vampires, werewolves use athletic events instead of violence to establish dominance over each other, most businesses stay open late at night for vampire customers, etc.).
The framework for the campaign is that we're part of a detective agency that specializes in 'weird stuff'. Besides my character Scott (a magician), his co-workers include Andy (Andrea), a ex-ROTC brat with some minor psychic abilities (the other PC), and Wendy, a Bast (cat-person) with some magical abilities of her own (NPC). So far we've (among other things) investigated the vamp dust trade, got involved in rivalries between different werewolf clans, helped to stop an airline hijacking attempt, investigated the theft of a sentient car, and had run-ins with a secret organization that has a serious hate for Scott, due to some stuff he did in one of his previous lives.