Okay, hear me out, an OSR-ish game of Post-Apocalyptic Cowboys of the Wastelands.
Post Apocalyptic Cowboys of the Wastelands (name very much a place holder).
Civilization in ruins, new diseases, mutated animals/plants, radiation/bio wastelands... But despite it all life goes on, people rise up to meet the challenge and to overcome!
Races:
Humans.- No noticeable mutations, but it's very unlikely there's a single non mutated human left.
The Scann (Psions) (Still searching for a name).- Mutated Humans whose mutation grants them psionic powers like telepathy, biokinesis, etc.
Cympanji (Elevated Ape).- It's unclear how but some of the great apes gained human like intelligence, it's suspected there might be other Elevated species but none have been encountered yet.
Gori.- Mutated Humans whose mutation gave them a rhinoceros like hide, a foot taller than "normal" Humans, stronger but also physically slower.
Classes:
Shaman-Healer-Medicine Man/Woman-Lore Keeper
Raider (As in tomb raider)
Hunter
Drifter
Tinkerer
It's just about 200 years after the fall, not all of humanity was thrown into the stone age if any (still not sure about that).
There's no lasers, light sabers, blasters, etc. (So far I'm putting the fall in the 21st century).