Looks really cool. Does this game also have playable splats or are all the factions enemies?
Not all the factions are "enemies". There are other groups besides the Invisible College, usually that came out of other cultures, who have very similar aims to the College.
But the IC rulebook does not have 'splats' for any groups aside from the Invisible College, only some general guidelines to the type of training these groups would have, and some NPC/opponent stats in the 'monster' section.
But in theory, somewhere down the road, I could imagine supplements that could expand on the structures and playable details of the other 'friendly' groups, some of the national Occult Intelligence divisions (I would love to do a sourcebook sometime about MI13, or The Kanaim), and maybe even some of the 'enemy' groups (the Choronzon Club would certainly be a laugh).