I wouldn't use the Wuhan Virus exactly in a game, but I've done RPGs with plagues before (magical, techno, natural) and to make them dangerous, they gotta be way more impressive than the sniffles. If its a real world-ish setting or hard-ish scifi, I go with a badass version of Hanta or Ebola. If its fantasy setting (or horror or space fantasy), then I like mutating viruses. Though the "grey goo" concept of nano-tech gone berserk would be pretty scary. That's something I'd use in a post-apoc setting.
My upcoming cyberpunk does address bio-weapons and plague issues, but I doubt I will be playtesting those scenarios out any time soon. After this nonsense passes, most gamers are going to want to escape far from it.
In fact, I wonder if our board game club will even play Pandemic for the next year or two!