I'm kind of tickled as to how the creators of Eclipse Phase managed to recreate the fundamental tension of Warhammer 40K, while decrying it as a concept. When your choices are to stand with the Nazi Ultimates and fascist Jovian junta, or to fall alone as humanity is swallowed by Exsurgent, or just Mr. Forkswarm deciding that the universe had Fucked Around enough and was now going to Find Out, what is your ideological purity worth to you?
It is, I find, a good little insight into how (or, sadly, if) people think about what they hate. The designers of Eclipse Phase believe that some ideas are so evil and repugnant that giving them a fair consideration, that doing anything but treating them like corruptive little mini-Exsurgents which can rip out people's ability to think and reason and ride them like a cordyceps polyp, presents actual, literal danger to life and limb. In-universe, the same justification applies, in far more detail and with far, far, far more justification, to every non-bioconservative faction. It was playing around with simulated (and thus enhancable) human intellects that made the Prometheans and caused the Fall.
Again, it's remarkable how the presence of the Jovians and the posthumans in conjunction with each other so cleanly make the point that there is no actual philosophical point here, just "We find X advancement neat and rad and only oppressive tyrants would keep it from the people, but obviously X+1 advancement is horrifying and dehumanizing and we should anarchistically purge any who make use of it."