Killed a bit of time in a local bookstore thumbing through The Wild Beyond the Witchlight adventure by WotC.
Contrary to some rumors, the monsters seem to feature alignment, but often preceeded by the word "typically" such as "typically chaotic evil." There were also named NPCs, including some oldies like Kelek the sorcereror, Ringlerun the wizard, Warduke the fashionably impaired, and more. All of these NPCs had alignments listed (without the "typically" bit, so apparently individual variations or waverings are still unstated just as they often have been).
Also, no signs of wheelchairs anywhere in the book that I could find on a 40-min flip-through.